Publications and Resources


Publications

  • Liangpunsakul S, Crabb DW. Early Detection of Alcoholic Liver Disease: Are We a Step Closer?. Gastroenterology. 2016 January;150(1):29-31. PubMed PMID: 26615116; PubMed Central PMCID: PMC5498077.
  • Crabb DW, Bataller R, Chalasani NP, Kamath PS, Lucey M, Mathurin P, McClain C, McCullough A, Mitchell MC, Morgan TR, Nagy L, Radaeva S, Sanyal A, Shah V, Szabo G. Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia. Gastroenterology. 2016 April;150(4):785-90. PubMed PMID: 26921783; PubMed Central PMCID: PMC5287362.
  • Liangpunsakul S, Puri P, Shah VH, Kamath P, Sanyal A, Urban T, Ren X, Katz B, Radaeva S, Chalasani N, Crabb DW. Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2016 December;14(12):1831-1838.e3. PubMed PMID: 27320325; PubMed Central PMCID: PMC5108670.
  • Jinjuvadia C, Jinjuvadia R, Mandapakala C, Durairajan N, Liangpunsakul S, Soubani AO. Trends in Outcomes, Financial Burden, and Mortality for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) in the United States from 2002 to 2010. COPD. 2017 February;14(1):72-79. PubMed PMID: 27419254; PubMed Central PMCID: PMC5626565.
  • Li W, Amet T, Xing Y, Yang D, Liangpunsakul S, Puri P, Kamath PS, Sanyal AJ, Shah VH, Katz BP, Radaeva S, Crabb DW, Chalasani N, Yu Q. Alcohol abstinence ameliorates the dysregulated immune profiles in patients with alcoholic hepatitis: A prospective observational study. Hepatology (Baltimore, Md.). 2017 August;66(2):575- 590. PubMed PMID: 28466561; PubMed Central PMCID: PMC5548491.
  • Beaudoin JJ, Long N, Liangpunsakul S, Puri P, Kamath PS, Shah V, Sanyal AJ, Crabb DW, Chalasani NP, Urban TJ. An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis. Scandinavian journal of gastroenterology. 2017 November;52(11):1263-1269. PubMed PMID: 28776448; PubMed Central PMCID: PMC5773288.
  • Beaudoin JJ, Long N, Liangpunsakul S, Puri P, Kamath PS, Shah V, Sanyal AJ, Crabb DW, Chalasani NP, Urban TJ. An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis. Scandinavian journal of gastroenterology. 2017 November;52(11):1263-1269. PubMed PMID: 28776448; PubMed Central PMCID: PMC5773288.
  • Comerford M, Lourens S, Liangpunsakul S, Chalasani NP, Sanyal AJ, Shah VH, Kamath PS, Puri P, Katz BP, Radaeva S, Crabb DW. Challenges in Patient Enrollment and Retention in Clinical Studies for Alcoholic Hepatitis: Experience of the TREAT Consortium. Alcoholism, clinical and experimental research. 2017 December;41(12):2000-2006. PubMed PMID: 28981151; PubMed Central PMCID: PMC5711577.
  • Liangpunsakul S, Beaudoin JJ, Shah VH, Puri P, Sanyal AJ, Kamath PS, Lourens SG, Tang Q, Katz BP, Crabb DW, Chalasani NP. Interaction between the patatin-like phospholipase domain-containing protein 3 genotype and coffee drinking and the risk for acute alcoholic hepatitis. Hepatology communications. 2018 January;2(1):29-34. PubMed PMID: 29404510; PubMed Central PMCID: PMC5776869.
  • Jinjuvadia R, Jinjuvadia C, Puangsricharoen P, Chalasani N, Crabb DW, Liangpunsakul S. Concomitant Psychiatric and Nonalcohol-Related Substance Use Disorders Among Final RPPR Page 8 Final RPPR DRAFT Hospitalized Patients with Alcoholic Liver Disease in the United States. Alcoholism, clinical and experimental research. 2018 February;42(2):397-402. PubMed PMID: 29197092; PubMed Central PMCID: PMC5785413.
  • Puri P, Liangpunsakul S, Christensen JE, Shah VH, Kamath PS, Gores GJ, Walker S, Comerford M, Katz B, Borst A, Yu Q, Kumar DP, Mirshahi F, Radaeva S, Chalasani NP, Crabb DW, Sanyal AJ. The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis. Hepatology (Baltimore, Md.). 2018 April;67(4):1284-1302. PubMed PMID: 29083504; PubMed Central PMCID: PMC5867221.
  • Samala N, Lourens SG, Shah VH, Kamath PS, Sanyal AJ, Crabb DW, Tang Q, Radaeva S, Liangpunsakul S, Chalasani N. Posttraumatic Stress Disorder in Patients with Heavy Alcohol Consumption and Alcoholic Hepatitis. Alcoholism, clinical and experimental research. 2018 October;42(10):1933-1938. PubMed PMID: 30080255; PubMed Central PMCID: PMC6167141.
  • Dasarathy S, Dasarathy J, Khiyami A, Joseph R, Lopez R, McCullough AJ. Validity of real time ultrasound in the diagnosis of hepatic steatosis: a prospective study. Journal of hepatology. 2009 December;51(6):1061-7. PubMed PMID: 19846234; PubMed Central PMCID: PMC6136148.
  • Chiang DJ, McCullough AJ. The impact of obesity and metabolic syndrome on alcoholic liver disease. Clinics in liver disease. 2014 February;18(1):157-63. PubMed PMID: 24274871; PubMed Central PMCID: PMC6130318.
  • Joshi-Barve S, Kirpich I, Cave MC, Marsano LS, McClain CJ. Alcoholic, Nonalcoholic, and Toxicant-Associated Steatohepatitis: Mechanistic Similarities and Differences. Cellular and molecular gastroenterology and hepatology. 2015 July;1(4):356-367. PubMed PMID: 28210688; PubMed Central PMCID: PMC5301292.
  • Guirguis J, Chhatwal J, Dasarathy J, Rivas J, McMichael D, Nagy LE, McCullough AJ, Dasarathy S. Clinical impact of alcohol-related cirrhosis in the next decade: estimates based on current epidemiological trends in the United States. Alcoholism, clinical and experimental research. 2015 November;39(11):2085-94. PubMed PMID: 26500036; PubMed Central PMCID: PMC4624492.
  • Dasarathy S. Cause and management of muscle wasting in chronic liver disease. Current opinion in gastroenterology. 2016 May;32(3):159-65. PubMed PMID: 26974417; PubMed Central PMCID: PMC5653274.
  • Goh GB, McCullough AJ. Natural History of Nonalcoholic Fatty Liver Disease. Digestive diseases and sciences. 2016 May;61(5):1226-33. PubMed PMID: 27003142.
  • Dasarathy S. Nutrition and Alcoholic Liver Disease: Effects of Alcoholism on Nutrition, Effects of Nutrition on Alcoholic Liver Disease, and Nutritional Therapies for Alcoholic Liver Disease. Clinics in liver disease. 2016 August;20(3):535-50. PubMed PMID: 27373615; PubMed Central PMCID: PMC4934388.
  • Dugum MF, McCullough AJ. Acute Alcoholic Hepatitis, the Clinical Aspects. Clinics in liver disease. 2016 August;20(3):499-508. PubMed PMID: 27373612; PubMed Central PMCID: PMC6130321.
  • Bukong TN, Iracheta-Vellve A, Saha B, Ambade A, Satishchandran A, Gyongyosi B, Lowe P, Catalano D, Kodys K, Szabo G. Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease. Hepatology (Baltimore, Md.). 2016 October;64(4):1057-71. PubMed PMID: 27302565; PubMed Central PMCID: PMC5033691.
  • Dasarathy S, Merli M. Sarcopenia from mechanism to diagnosis and treatment in liver disease. Journal of hepatology. 2016 December;65(6):1232-1244. PubMed PMID: 27515775; PubMed Central PMCID: PMC5116259.
  • Mitchell MC, Friedman LS, McClain CJ. Medical Management of Severe Alcoholic Hepatitis: Expert Review from the Clinical Practice Updates Committee of the AGA Institute. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2017 January;15(1):5-12. PubMed PMID: 27979049; PubMed Central PMCID: PMC5172399.
  • Lowe PP, Gyongyosi B, Satishchandran A, Iracheta-Vellve A, Ambade A, Kodys K, Catalano D, Ward DV, Szabo G. Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice. PloS one. 2017 March 28;12(3):e0174544. PubMed PMID: 28350851; PubMed Central PMCID: PMC5370121.
  • Dasarathy S, Mookerjee RP, Rackayova V, Rangroo Thrane V, Vairappan B, Ott P, Rose CF. Ammonia toxicity: from head to toe?. Metabolic brain disease. 2017 April;32(2):529-538. PubMed PMID: 28012068.
  • Kirpich IA, McClain CJ, Vatsalya V, Schwandt M, Phillips M, Falkner KC, Zhang L, Harwell C, George DT, Umhau JC. Liver Injury and Endotoxemia in Male and Female Alcohol-Dependent Individuals Admitted to an Alcohol Treatment Program. Alcoholism, clinical and experimental research. 2017 April;41(4):747-757. PubMed PMID: 28166367; PubMed Central PMCID: PMC5378598.
  • Aday AW, Mitchell MC, Casey LC. Alcoholic hepatitis: current trends in management. Current opinion in gastroenterology. 2017 May;33(3):142-148. PubMed PMID: 28282320.
  • Dasarathy S, Brown JM. Alcoholic Liver Disease on the Rise: Interorgan Cross Talk Driving Liver Injury. Alcoholism, clinical and experimental research. 2017 May;41(5):880- 882. PubMed PMID: 28295407; PubMed Central PMCID: PMC5405002.
  • Arriazu E, Ge X, Leung TM, Magdaleno F, Lopategi A, Lu Y, Kitamura N, Urtasun R, Theise N, Antoine DJ, Nieto N. Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to liver injury. Gut. 2017 June;66(6):1123- 1137. PubMed PMID: 26818617; PubMed Central PMCID: PMC5532463.
  • Kumar A, Davuluri G, Silva RNE, Engelen MPKJ, Ten Have GAM, Prayson R, Deutz NEP, Dasarathy S. Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis. Hepatology (Baltimore, Md.). 2017 June;65(6):2045-2058. PubMed PMID: 28195332; PubMed Central PMCID: PMC5444955.
  • McClain C, Vatsalya V, Cave M. Role of Zinc in the Development/Progression of Alcoholic Liver Disease. Current treatment options in gastroenterology. 2017 June;15(2):285-295. PubMed PMID: 28447197; PubMed Central PMCID: PMC6206836.
  • Dasarathy S. Are Exercise Benefits in Nonalcoholic Fatty Liver Disease Due to Increased Autophagy?. Exercise and sport sciences reviews. 2017 July;45(3):125. PubMed PMID: 28622190; PubMed Central PMCID: PMC5505627.
  • Iracheta-Vellve A, Petrasek J, Gyogyosi B, Bala S, Csak T, Kodys K, Szabo G. Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice. Liver international : official journal of the International Association for the Study of the Liver. 2017 July;37(7):968-973. PubMed PMID: 28345165; PubMed Central PMCID: PMC5479767.
  • Dasarathy J, McCullough AJ, Dasarathy S. Sarcopenia in Alcoholic Liver Disease: Clinical and Molecular Advances. Alcoholism, clinical and experimental research. 2017 August;41(8):1419-1431. PubMed PMID: 28557005; PubMed Central PMCID: PMC5553706.
  • Szabo G, Momen-Heravi F. Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets. Nature reviews. Gastroenterology & hepatology. 2017 August;14(8):455-466. PubMed PMID: 28634412.
  • Wei X, Shi B, Koo I, Yin X, Lorkiewicz P, Suhail H, Rattan R, Giri S, McClain CJ, Zhang X. Analysis of stable isotope assisted metabolomics data acquired by GC-MS. Analytica chimica acta. 2017 August 8;980:25-32. PubMed PMID: 28622800; PubMed Central PMCID: PMC5541907.
  • Horvath B, Allende D, Xie H, Guirguis J, Jeung J, Lapinski J, Patil D, McCullough AJ, Dasarathy S, Liu X. Interobserver Variability in Scoring Liver Biopsies with a Diagnosis of Alcoholic Hepatitis. Alcoholism, clinical and experimental research. 2017 September;41(9):1568-1573. PubMed PMID: 28654190.
  • Gustot T, Fernandez J, Szabo G, Albillos A, Louvet A, Jalan R, Moreau R, Moreno C. Sepsis in alcohol-related liver disease. Journal of hepatology. 2017 November;67(5):1031-1050. PubMed PMID: 28647569.
  • Lindenmeyer CC, McCullough AJ. The Natural History of Nonalcoholic Fatty Liver Disease-An Evolving View. Clinics in liver disease. 2018 February;22(1):11-21. PubMed PMID: 29128051; PubMed Central PMCID: PMC6130315.
  • Prodhan MAI, Yin X, Kim S, McClain C, Zhang X. Surface fitting for calculating the second dimension retention index in comprehensive two-dimensional gas chromatography mass spectrometry. Journal of chromatography. A. 2018 March 2;1539:62-70. PubMed PMID: 29395161; PubMed Central PMCID: PMC5826898.
  • Saha B, Momen-Heravi F, Furi I, Kodys K, Catalano D, Gangopadhyay A, Haraszti R, Satishchandran A, Iracheta-Vellve A, Adejumo A, Shaffer SA, Szabo G. Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90. Hepatology (Baltimore, Md.). 2018 May;67(5):1986-2000. PubMed PMID: 29251792; PubMed Central PMCID: PMC5906190.
  • Ge X, Arriazu E, Magdaleno F, Antoine DJ, Dela Cruz R, Theise N, Nieto N. High Mobility Group Box-1 Drives Fibrosis Progression Signaling via the Receptor for Advanced Glycation End Products in Mice. Hepatology (Baltimore, Md.). 2018 May 18. PubMed PMID: 29774570; PubMed Central PMCID: PMC6240507.
  • He L, Prodhan MAI, Yuan F, Yin X, Lorkiewicz PK, Wei X, Feng W, McClain C, Zhang X. Simultaneous quantification of straight-chain and branched-chain short chain fatty acids by gas chromatography mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2018 August 15;1092:359-367. PubMed PMID: 29936372; PubMed Central PMCID: PMC6190712.
  • Hajifathalian K, Torabi Sagvand B, McCullough AJ. Effect of Alcohol Consumption on Survival in Nonalcoholic Fatty Liver Disease: A National Prospective Cohort Study. Hepatology (Baltimore, Md.). 2018 August 19. PubMed PMID: 30125379.
  • EASL Clinical Practice Guidelines on nutrition in chronic liver disease. Journal of hepatology. 2018 August 22. PubMed PMID: 30144956.
  • Vatsalya V, Kong M, Cave MC, Liu N, Schwandt ML, George DT, Ramchandani VA, McClain CJ. Association of serum zinc with markers of liver injury in very heavy drinking alcohol-dependent patients. The Journal of nutritional biochemistry. 2018 September;59:49-55. PubMed PMID: 29960116; PubMed Central PMCID: PMC6129416.
  • Ambade A, Lowe P, Kodys K, Catalano D, Gyongyosi B, Cho Y, Iracheta Vellve A, Adejumo A, Saha B, Calenda C, Mehta J, Lefebvre E, Vig P, Szabo G. Pharmacological inhibition of CCR2/5 signaling prevents and reverses alcohol-induced liver damage, steatosis and inflammation in mice. Hepatology (Baltimore, Md.). 2018 September 4. PubMed PMID: 30179264.

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AlcHepNet is a clinical and translational research initiative funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), a division of NIH.